Description

Oxirane, (Phenylmethoxy)-, (R)- (9Ci) is a chiral epoxide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical control is critical. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical producers focused on asymmetric synthesis and chiral resolution technologies.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for active pharmaceutical ingredients (APIs) requiring specific (R)-configuration, particularly in cardiovascular and central nervous system drugs.
• Agrochemical Building Block: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis (e.g., for epoxidation or hydroxylation reactions).
• Fine Chemical and Flavor/Fragrance Production: Employed in the multi-step synthesis of complex, high-value aroma chemicals and specialty flavors.
• Polymer Modification: Used to introduce chiral phenylmethoxy groups into polymer backbones for materials with specific optical or mechanical properties.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	Oxirane, (Phenylmethoxy)-, (R)- (9Ci)
CAS No.	119142-17-5
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(R)-Phenylglycidyl Ether; (R)-(-)-Phenyl Glycidyl Ether; (R)-2-[(Phenylmethoxy)methyl]oxirane; (R)-1,2-Epoxy-3-(phenylmethoxy)propane; (R)-Benzyl Glycidyl Ether; (R)-BGE; (R)-α-Epoxybenzyl Ether; (2R)-2-[(Phenylmethoxy)methyl]oxirane
EINECS	Contact for details

Quality Control

Our Oxirane, (Phenylmethoxy)-, (R)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including chiral HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.520 - 1.525
Specific Rotation ([α]20D)	-30° to -35° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.