Description

4-(Dimethylamino)-2-Butynoic Acid is a versatile alkyne-containing carboxylic acid derivative that serves as a key building block in advanced organic synthesis. Its unique structure, featuring both a terminal alkyne and a tertiary amine, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as click chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of complex drug candidates, particularly those requiring alkyne-azide cycloaddition (click chemistry) for bioconjugation or probe development.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, where its functional groups allow for the introduction of specific bioactive moieties.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functional polymers, dendrimers, and advanced materials with tailored properties.
• Bioconjugation and Probe Chemistry: The alkyne group is ideal for Huisgen 1,3-dipolar cycloaddition reactions with azides, enabling the labeling of biomolecules for diagnostics and imaging.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-(Dimethylamino)-2-Butynoic Acid
CAS No.	118764-05-9
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	2-Butynoic acid, 4-(dimethylamino)-; 4-Dimethylamino-2-butynoic acid; 4-(N,N-Dimethylamino)but-2-ynoic acid; DMABA; (Dimethylamino)butynoic acid; N,N-Dimethyl-2-butynoic acid-4-amine; 4-(Dimethylamino)but-2-ynoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(Dimethylamino)-2-Butynoic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and fine chemical applications. Comprehensive analytical testing, including HPLC, NMR, and FTIR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.