Description

Di-tert-Butylphosphonite/Biphenyl is a specialized organophosphorus compound that serves as a highly effective ligand and catalyst precursor in advanced chemical synthesis. Its value lies in its ability to facilitate challenging cross-coupling and phosphorylation reactions with high selectivity and yield. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for developing new active ingredients and functional polymers.

Application

• As a key ligand in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi).
• As a precursor for generating active palladium and nickel catalysts used in C-C and C-P bond formation.
• In the synthesis of pharmaceutical intermediates, particularly for complex molecules requiring phosphonate or phosphonite functionalities.
• For the development of agrochemicals, including herbicides and plant growth regulators.
• In materials science for the preparation of flame retardants and specialized polymer additives.
• In organic light-emitting diode (OLED) research as a building block for electron-transport materials.
• For academic and industrial R&D in novel organophosphorus chemistry.

Basic Information

Product Name	Di-tert-Butylphosphonite/Biphenyl
CAS No.	118578-01-1
Molecular Formula	C20H29OP
Molecular Weight	316.42 g/mol
Synonyms	Di-tert-butyl(phenyl)phosphonite; Biphenyl Di-tert-butylphosphonite; (Biphenyl-2-yl)di-tert-butylphosphonite; P,P-Di-tert-butyl-P-phenylphosphonite; Di-tert-butyl phenylphosphonite; Phosphonous acid, P-phenyl-, P,P-bis(1,1-dimethylethyl) ester; 2-(Di-tert-butylphosphino)biphenyl precursor
EINECS	Contact for details

Quality Control

Every batch of our Di-tert-Butylphosphonite/Biphenyl is manufactured and tested under strict quality management protocols to ensure consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, making it suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.