Description

(4-Fluorophenyl)-Pyrazin-2-Ylmethanone is a high-purity fluorinated heterocyclic building block with the CAS registry number 118543-82-1. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorophenyl and pyrazine motifs for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials and liquid crystals due to its conjugated system.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(4-Fluorophenyl)-Pyrazin-2-Ylmethanone
CAS No.	118543-82-1
Molecular Formula	C11H7FN2O
Molecular Weight	202.19 g/mol
Synonyms	2-(4-Fluorobenzoyl)pyrazine; 1-(4-Fluorophenyl)-2-pyrazinyl-ethanone; 4-Fluorophenyl 2-pyrazinyl ketone; (4-Fluorobenzoyl)pyrazine; Pyrazin-2-yl(4-fluorophenyl)methanone; 118543-82-1; 4-Fluorobenzoylpyrazine
EINECS	Contact for details

Quality Control

Our (4-Fluorophenyl)-Pyrazin-2-Ylmethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.