Description

(18β,20α)-Glycyrrhizic Acid CAS NO 118441-85-3 is a specific stereoisomer of glycyrrhizic acid, a key bioactive triterpenoid saponin derived from licorice root. This high-purity compound is valued for its potent biological activities, including anti-inflammatory, antiviral, and hepatoprotective properties, making it a critical intermediate for advanced research and development. It is essential for pharmaceutical manufacturers, nutraceutical formulators, and research institutions focused on developing novel therapeutics, functional foods, and high-end cosmetic ingredients.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or active pharmaceutical ingredient (API) in the synthesis of anti-inflammatory, antiviral, and hepatoprotective drugs.
• Nutraceuticals & Functional Foods: Incorporated into dietary supplements and health foods for its liver-supporting and immune-modulating benefits.
• Cosmetic & Skincare Formulations: Used in high-performance skincare products for its soothing, anti-irritant, and skin-brightening effects.
• Biomedical Research: A vital reference standard and investigational compound in pharmacological, toxicological, and metabolic pathway studies.
• Traditional Medicine Enhancement: Employed to standardize and potentiate licorice-based herbal extracts and formulations.
• Veterinary Pharmaceuticals: Applied in animal health products for its therapeutic properties.

Basic Information

Product Name	(18β,20α)-Glycyrrhizic Acid
CAS No.	118441-85-3
Molecular Formula	C42H62O16
Molecular Weight	822.92 g/mol
Synonyms	Glycyrrhizic Acid (18β,20α-isomer); (18β,20α)-3β-({2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl}oxy)-11-oxoolean-12-en-29-oic acid; 18-beta,20-α-Glycyrrhizic Acid; Enoxolone 3-O-(2-O-β-D-glucopyranuronosyl-α-D-glucopyranuronoside); Licorice Saponin G2; Glycyrrhizin (specific isomer); UR-1; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our (18β,20α)-Glycyrrhizic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.