Description

5,5,5-Trifluoro-2-Oxopentanoic Acid is a versatile fluorinated keto acid building block. This compound is valued for its unique trifluoromethyl group, which imparts enhanced metabolic stability and lipophilicity to target molecules. It is primarily used by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of protease inhibitors, kinase inhibitors, and other bioactive molecules containing a trifluoromethyl ketone moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the CF3 group can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for synthesizing fluorinated polymers, liquid crystals, or specialty coatings with tailored properties.
• Biochemical Probe Development: Employed in medicinal chemistry to create activity-based probes for studying enzyme mechanisms and function.
• Organic Synthesis Building Block: Utilized in various carbon-carbon bond forming reactions, such as aldol condensations, to introduce fluorinated segments.

Basic Information

Product Name	5,5,5-Trifluoro-2-Oxopentanoic Acid
CAS No.	118311-18-5
Molecular Formula	C5H5F3O3
Molecular Weight	170.09 g/mol
Synonyms	5,5,5-Trifluoro-2-oxopentanoic acid; 5,5,5-Trifluoro-4-oxopentanoic acid; 4,4,4-Trifluoro-3-oxobutane-1-carboxylic acid; 3-Oxo-5,5,5-trifluoropentanoic acid; 5,5,5-Trifluoro-4-oxopentanoic acid; 4,4,4-Trifluoroacetoacetic acid; Levulinic acid, 5,5,5-trifluoro-; 5,5,5-Trifluorolevulinic acid
EINECS	Contact for details

Quality Control

Our 5,5,5-Trifluoro-2-Oxopentanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its nature as a strong acid/organic solvent, it should be kept away from incompatible materials such as bases, oxidizing agents, and reactive metals. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.