Description

1-Boc-3-Piperidinecarboxaldehyde is a versatile and high-purity chemical building block, essential for advanced organic synthesis. Its primary value lies in its role as a protected aldehyde intermediate, enabling the controlled introduction of the piperidine moiety into complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-containing drug candidates, including kinase inhibitors, receptor antagonists, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the piperidine scaffold contributes to biological activity.
• Peptidomimetics & PROTACs: Serves as a crucial building block for creating peptide mimics and Proteolysis Targeting Chimeras (PROTACs) in medicinal chemistry.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of functionalized polymers and advanced organic materials with specific properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-Boc-3-Piperidinecarboxaldehyde
CAS No.	118156-93-7
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	tert-Butyl 3-formylpiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-piperidinecarboxaldehyde; 3-Formyl-1-piperidinecarboxylic acid tert-butyl ester; 1-Boc-3-formylpiperidine; N-Boc-3-piperidinecarboxaldehyde; 1-N-Boc-3-piperidinecarboxaldehyde; 3-Piperidinecarboxaldehyde, 1-(1,1-dimethylethoxy)carbonyl]-; Boc-3-piperidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Piperidinecarboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.