Description

Cyclobutaneacetic Acid, 3-(Chloroacetyl)-2,2-Dimethyl-, cis- (9Ci) is a high-purity, specialized organic intermediate featuring a unique cyclobutane ring system functionalized with acetic acid and chloroacetyl groups. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise stereochemistry and functional group handles for advanced chemical transformations. It is primarily needed by research and development teams within the pharmaceutical and agrochemical industries, where it serves as a key precursor for novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the cis-configuration and cyclobutane core contribute to specific biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of novel polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in organic chemistry research for constructing complex, chelating ligands used in asymmetric catalysis.
• Fine Chemical Production: Acts as a versatile intermediate for the custom synthesis of specialty chemicals used in flavors, fragrances, and electronic materials.

Basic Information

Product Name	Cyclobutaneacetic Acid, 3-(Chloroacetyl)-2,2-Dimethyl-, cis- (9Ci)
CAS No.	118147-73-2
Molecular Formula	C10H15ClO3
Molecular Weight	218.68 g/mol
Synonyms	cis-3-(Chloroacetyl)-2,2-dimethylcyclobutaneacetic acid; (1R,3S)-3-(Chloroacetyl)-2,2-dimethylcyclobutaneacetic acid; 2,2-Dimethyl-3-(2-chloroacetyl)cyclobutaneacetic acid, cis-; 3-(Chloroacetyl)-2,2-dimethylcyclobutanecarboxylic acid (cis isomer); Cyclobutanecarboxylic acid, 3-(chloroacetyl)-2,2-dimethyl-, cis-; (1S,3R)-rel-3-(Chloroacetyl)-2,2-dimethylcyclobutaneacetic acid
EINECS	Contact for details

Quality Control

Our Cyclobutaneacetic Acid, 3-(Chloroacetyl)-2,2-Dimethyl-, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.