Description

3-Hydroxy-3-(Trifluoromethyl)Cyclohexene is a versatile fluorinated organic intermediate of significant interest in advanced chemical synthesis. Its unique structure, featuring both a hydroxyl group and a trifluoromethyl group on a cyclohexene ring, makes it a valuable building block for introducing fluorine-containing motifs into target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with tailored surface properties or specific refractive indices.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fluorine Chemistry Research: A fundamental substrate in academic and industrial research exploring new methodologies for C-F bond formation and the stereoselective functionalization of fluorinated cyclohexenes.

Basic Information

Product Name	3-Hydroxy-3-(Trifluoromethyl)Cyclohexene
CAS No.	118143-28-5
Molecular Formula	C7H9F3O
Molecular Weight	166.14 g/mol
Synonyms	3-(Trifluoromethyl)cyclohex-3-en-1-ol; 3-Hydroxy-3-(trifluoromethyl)-1-cyclohexene; 3-Trifluoromethyl-3-cyclohexen-1-ol; 1-Cyclohexene-3-ol, 3-(trifluoromethyl)-; 3-Cyclohexene-1-ol, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-3-(Trifluoromethyl)Cyclohexene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.