Description

1,3-Dioxolane, 2-(2,2,2-Trifluoroethyl)- is a specialized fluorinated cyclic acetal, a high-value building block in advanced organic synthesis. Its unique structure, featuring a dioxolane ring and a trifluoroethyl side chain, makes it a critical intermediate for introducing fluorine-containing motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise fluorination to modify the properties of their products. The CAS number for this substance is 117971-08-1.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing trifluoroethyl ether or acetal functionalities that can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom improves lipophilicity and biological activity.
• Liquid Crystal & Electronic Materials: Acts as a precursor for fluorine-containing compounds used in liquid crystal displays (LCDs) and dielectric materials.
• Polymer & Resin Modifier: Employed to synthesize fluorinated monomers or cross-linkers that impart special properties like chemical resistance, low surface energy, or altered refractive index to polymers.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocycles and facilitating protective group chemistry in multi-step synthetic routes.
• Research & Development: Critical for academic and industrial R&D focused on fluorochemistry, medicinal chemistry, and new material discovery.

Basic Information

Product Name	1,3-Dioxolane, 2-(2,2,2-Trifluoroethyl)-
CAS No.	117971-08-1
Molecular Formula	C5H7F3O2
Molecular Weight	156.10 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)-1,3-dioxolane; 2-(Trifluoroethyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(trifluoroethyl)-; α-(Trifluoroethyl)-1,3-dioxolane; Trifluoroethyl dioxolane; 2-Trifluoroethyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 2-(2,2,2-Trifluoroethyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials. For long-term storage, maintaining the container under an inert atmosphere (e.g., nitrogen) is recommended to preserve stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.