Description

1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Carbaldehyde is a high-purity organic building block featuring a pyrrole core functionalized with a tosyl protecting group and an aldehyde moiety. This compound is a critical intermediate in modern synthetic organic chemistry, enabling the construction of complex heterocyclic frameworks. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of pyrrole-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the biological activity of the pyrrole heterocycle.
• Material Science: Serves as a precursor for functional polymers, organic semiconductors, and ligands for catalytic systems.
• Academic & R&D: Employed in methodological studies for palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions.
• Fine Chemical Synthesis: Utilized for the preparation of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Carbaldehyde
CAS No.	117954-70-8
Molecular Formula	C12H11NO3S
Molecular Weight	249.29 g/mol
Synonyms	1H-Pyrrole-3-carboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosyl-1H-pyrrole-3-carbaldehyde; 3-Formyl-1-tosylpyrrole; 1-(p-Toluenesulfonyl)-1H-pyrrole-3-carboxaldehyde; 1-Tosylpyrrole-3-carboxaldehyde; N-Tosylpyrrole-3-carboxaldehyde; 1-(4-Methylbenzenesulfonyl)-1H-pyrrole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.