Description

(E)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)But-3-En-2-Ol is a high-value, protected boronic ester derivative featuring a terminal alcohol functional group. This compound is a crucial synthetic intermediate in modern organic chemistry, prized for its stability and reactivity in cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for constructing complex biaryl and conjugated systems in medicinal chemistry and material science.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organometallic catalysts.
• Polymer and Material Science: Incorporated into the backbone of specialty polymers, OLED materials, and liquid crystals.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Agrochemical Research: Acts as an intermediate in the development of new herbicides and fungicides.

Basic Information

Product Name	(E)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)But-3-En-2-Ol
CAS No.	117924-31-9
Molecular Formula	C10H19BO3
Molecular Weight	198.07 g/mol
Synonyms	(E)-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol; 2-Buten-2-ol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, (E)-; (E)-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-buten-2-ol; trans-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol; Pinacol (E)-4-hydroxybut-2-enylboronate
EINECS	Contact for details

Quality Control

Every batch of (E)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)But-3-En-2-Ol is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Isomeric Purity (E/Z Ratio)	≥95:5 (E:Z)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.