Description

12-Deoxy-16-Hydroxyphorbol-4'-(12',14'-Butadienyl)-6'-(16',18',20'-Nonatrienyl)-Bicyclo(3.1.0)Hexane-(13-O)-2'-(Carboxylate)-(16-O)-3'-(8'-Butenoic-10')Ate is a complex diterpene ester derivative, structurally related to phorbol, known for its intricate molecular architecture. This compound is of significant interest in advanced organic synthesis and pharmacological research due to its unique functional groups and stereochemistry. It serves as a valuable high-purity reference standard and key synthetic intermediate for researchers and developers in pharmaceutical discovery, agrochemical development, and specialized chemical synthesis.

Application

• Pharmaceutical Research & Development: Used as a reference standard or a sophisticated building block in the synthesis of novel drug candidates, particularly in oncology and inflammation-related pathways.
• Agrochemical Innovation: Serves as a precursor or model compound in the development of new plant growth regulators or bioactive agents with specific modes of action.
• Academic & Institutional Research: A critical tool for studying diterpene biosynthesis, structure-activity relationships (SAR), and complex natural product chemistry.
• Chemical Synthesis: Acts as a challenging and high-value intermediate for synthetic organic chemists working on complex, polycyclic molecular frameworks.
• Biochemical Probes: Potential use in developing probes to study specific enzyme interactions or cellular signaling pathways modulated by phorbol-related structures.

Basic Information

Item	Detail
Product Name	12-Deoxy-16-Hydroxyphorbol-4'-(12',14'-Butadienyl)-6'-(16',18',20'-Nonatrienyl)-Bicyclo(3.1.0)Hexane-(13-O)-2'-(Carboxylate)-(16-O)-3'-(8'-Butenoic-10')Ate
CAS No.	117855-87-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	12-Deoxy-16-hydroxyphorbol 13-acetate 20-(8-butenoate); Phorbol-13-acetate-20-(8-butenoate) derivative; 12-Deoxy-16-hydroxyphorbol derivative; CAS 117855-87-5; 4'-(12',14'-Butadienyl)-6'-(16',18',20'-Nonatrienyl)phorbol ester; Complex diterpene phorbol ester; 12-Deoxy-16-Hydroxyphorbol butadienyl nonatrienyl ester
EINECS	Contact for details

Quality Control

Every batch of 12-Deoxy-16-Hydroxyphorbol-4'-(12',14'-Butadienyl)-6'-(16',18',20'-Nonatrienyl)-Bicyclo(3.1.0)Hexane-(13-O)-2'-(Carboxylate)-(16-O)-3'-(8'-Butenoic-10')Ate is produced and handled under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, consider storage at 2-8°C under an inert atmosphere. Keep the container tightly sealed in a dry environment to protect the compound's integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.