Description

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,11,13- Pentahydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6- azacyclopentadecan-15-one is a complex, stereochemically defined macrolide compound of significant interest in advanced chemical synthesis. This molecule matters as a sophisticated chiral building block or potential intermediate for the development of novel pharmaceuticals and bioactive agents. It is primarily needed by research and development organizations in the pharmaceutical, agrochemical, and fine chemical sectors for use in asymmetric synthesis, medicinal chemistry programs, and the production of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for macrolide-derived therapeutics.
• Medicinal Chemistry Research: Used as a scaffold or precursor in drug discovery for probing structure-activity relationships (SAR) and developing novel bioactive molecules.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective synthesis due to its multiple defined chiral centers.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals and flavors/fragrances.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with specific biological activity.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study biological pathways and mechanisms.

Basic Information

Product Name	(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,11,13-Pentahydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
CAS No.	117693-42-2
Molecular Formula	C20H39NO7
Molecular Weight	405.53 g/mol
Synonyms	2-Ethyl-3,4,10,11,13-pentahydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-rel-2-Ethyl-3,4,10,11,13-pentahydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one; Macrolide derivative CAS 117693-42-2; 1-Oxa-6-azacyclopentadecan-15-one derivative; Polyhydroxylated macrolactam
EINECS	Contact for details

Quality Control

Our (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,11,13-pentahydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.