Description

Diethyl 2-(But-3-Ynyl)Malonate is a specialized malonate ester derivative featuring a terminal alkyne functional group. This unique bifunctional structure makes it a highly versatile and valuable building block in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne or malonate-derived frameworks.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Click Chemistry: The terminal alkyne group enables efficient Huisgen cycloaddition (click) reactions for bioconjugation and polymer functionalization.
• Organic Synthesis Building Block: Utilized in Michael additions, alkylations, and cyclization reactions to construct complex heterocycles and carbon chains.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of specific ester-based aroma compounds.

Basic Information

Product Name	Diethyl 2-(But-3-Ynyl)Malonate
CAS No.	117500-15-9
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	Diethyl (but-3-yn-1-yl)malonate; 2-(But-3-yn-1-yl)propanedioic acid diethyl ester; Diethyl but-3-ynylmalonate; But-3-ynylmalonic acid diethyl ester; 3-Butynylmalonic Acid Diethyl Ester; Propanedioic acid, 2-(3-butyn-1-yl)-, diethyl ester; Diethyl 2-(3-Butynyl)malonate
EINECS	Contact for details

Quality Control

Our Diethyl 2-(But-3-Ynyl)Malonate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting R&D and process chemistry requirements. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep container tightly sealed under an inert atmosphere for optimal shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.430 - 1.440
Density	1.02 - 1.06 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.