Description

3,4-Di-o-Acetyl-6-o-(tert-Butyldimethylsilyl)-D-Glucal is a sophisticated, high-purity carbohydrate derivative and a key protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemical control in the construction of complex molecules. It is primarily utilized in the pharmaceutical industry for the synthesis of novel glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs), including antiviral and anticancer agents.
• Glycoscience Research: Used in academic and industrial R&D for studying glycosylation reactions and developing new glycosylation methodologies.
• Glycoconjugate Synthesis: Serves as a protected donor substrate for the preparation of oligosaccharides, glycopeptides, and glycolipids.
• Enzyme Inhibitor Development: A precursor in the creation of potent and selective glycosidase inhibitors for therapeutic and diagnostic applications.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged carbohydrate probes for studying biological recognition processes.
• Process Chemistry: Used in scale-up and process development for the commercial manufacturing of carbohydrate-derived drugs.

Basic Information

Product Name	3,4-Di-o-Acetyl-6-o-(tert-Butyldimethylsilyl)-D-Glucal
CAS No.	117136-33-1
Molecular Formula	C16H28O6Si
Molecular Weight	344.48 g/mol
Synonyms	6-O-(tert-Butyldimethylsilyl)-3,4-di-O-acetyl-D-glucal; 3,4-Di-O-acetyl-6-O-(tert-butyldimethylsilyl)-D-glucal; D-Glucal, 3,4-di-O-acetyl-6-O-[(1,1-dimethylethyl)dimethylsilyl]-; 6-O-TBDMS-3,4-di-O-acetyl-D-glucal; 3,4-Di-O-acetyl-6-O-TBDMS-D-glucal; 1,5-Anhydro-2-deoxy-3,4-di-O-acetyl-6-O-(tert-butyldimethylsilyl)-D-arabino-hex-1-enitol
EINECS	Contact for details

Quality Control

Our 3,4-Di-o-Acetyl-6-o-(tert-Butyldimethylsilyl)-D-Glucal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.