Description

[(2R,3R)-3-Benzyloxiran-2-Yl]Methanol CAS NO 116949-62-3 is a high-purity chiral epoxide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and reactive oxirane ring make it a valuable building block for constructing complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, including potential antiviral, cardiovascular, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality enhances biological activity and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical and Flavor/Fragrance Ingredient: Employed in the multi-step synthesis of complex aroma chemicals and specialty fine chemicals requiring precise stereochemical control.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic synthesis and stereochemistry research.

Basic Information

Product Name	[(2R,3R)-3-Benzyloxiran-2-Yl]Methanol
CAS No.	116949-62-3
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(2R,3R)-2-(Hydroxymethyl)-3-phenyloxirane; (2R,3R)-3-Phenylglycidol; (2R,3R)-3-Phenyloxiran-2-ylmethanol; (2R,3R)-(-)-3-Phenylglycidol; (2R,3R)-3-Benzyl-2-(hydroxymethyl)oxirane; trans-3-Phenylglycidol; Benzyloxiranemethanol (stereospecific)
EINECS	Contact for details

Quality Control

Our [(2R,3R)-3-Benzyloxiran-2-Yl]Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.