Description

1-(2-Fluorophenyl)-2-Methylpropan-1-One is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research, offering a versatile reactive site for further functionalization. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with fluorinated aromatic moieties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorophore-tagged molecules and activity-based probes for biochemical studies.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-(2-Fluorophenyl)-2-Methylpropan-1-One
CAS No.	116707-09-6
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	2-Fluoro-α,α-dimethylbenzeneacetaldehyde; 2'-Fluoro-2-methylpropiophenone; 1-(2-Fluorophenyl)-2-methyl-1-propanone; o-Fluoro-α,α-dimethylacetophenone; 2-Fluorophenyl isobutyl ketone; Isobutyl 2-fluorophenyl ketone; α,α-Dimethyl-2-fluorophenylacetaldehyde
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-2-Methylpropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.