Description

1-Chloro-3-Iodo-5-Methyl-Benzene is a halogenated aromatic compound of significant interest in advanced organic synthesis. This versatile building block is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its halogen substituents for structural diversity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of both chloro and iodo groups, allowing for sequential functionalization.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex organic molecules, including natural product analogs and dyes.
• Ligand and Catalyst Development: Used to create novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-Chloro-3-Iodo-5-Methyl-Benzene
CAS No.	116632-43-0
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	3-Chloro-5-Iodotoluene; 5-Chloro-3-Iodotoluene; 1-Chloro-3-iodo-5-methylbenzene; 3-Iodo-5-chlorotoluene; 5-Methyl-1-chloro-3-iodobenzene; Toluene, 3-chloro-5-iodo-; Benzene, 1-chloro-3-iodo-5-methyl-
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Iodo-5-Methyl-Benzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.