Description

3-Chloro-4-Iodotoluene is a halogenated aromatic compound of significant interest in advanced organic synthesis. Its value lies in its dual functionalization, serving as a versatile building block for constructing complex molecular architectures. This intermediate is particularly needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores for bioactivity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the chloro-iodo substitution pattern is critical.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Chemical Synthesis: A versatile substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Laboratory Reagent: Used in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	3-Chloro-4-Iodotoluene
CAS No.	116632-42-9
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	1-Chloro-2-iodo-4-methylbenzene; 3-Chloro-4-iodo-1-methylbenzene; 4-Methyl-3-chloroiodobenzene; Toluene, 3-chloro-4-iodo-; 3-Chloro-4-iodotoluene; 2-Iodo-5-chlorotoluene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Iodotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant enclosures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.