Description

2-Chloro-5-Iodotoluene is a halogenated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on a toluene backbone, makes it a valuable precursor for constructing complex molecules through selective cross-coupling reactions. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactivity for creating complex molecular architectures.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and methodologies.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Chloro-5-Iodotoluene
CAS No.	116632-41-8
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	1-Chloro-2-methyl-4-iodobenzene; 2-Methyl-4-iodochlorobenzene; 4-Iodo-2-chlorotoluene; 2-Chloro-4-iodotoluene; 2-Chloro-5-iodo-1-methylbenzene; Toluene, 2-chloro-5-iodo-; 5-Iodo-2-chlorotoluene
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodotoluene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.