Description

1-Iodo-2-Chloro-3-Methyl-Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique substitution pattern, which provides distinct reactivity and steric properties for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications such as catalyst development and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides due to its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Catalyst & Ligand Development: Employed in the creation of novel organometallic catalysts and ligands for asymmetric synthesis and other catalytic processes.
• Chemical Research: A versatile building block for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions in academic and industrial laboratories.
• Dye & Pigment Intermediate: Used in the synthesis of complex halogenated dyes and organic pigments.

Basic Information

Product Name	1-Iodo-2-Chloro-3-Methyl-Benzene
CAS No.	116632-40-7
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	2-Chloro-1-iodo-3-methylbenzene; 2-Chloro-3-methyl-1-iodobenzene; 3-Methyl-2-chloroiodobenzene; 1-Chloro-2-iodo-3-methylbenzene (isomer); 2-Chloro-3-methylphenyl iodide; o-Chloro-m-methyl iodobenzene; Halogenated toluene derivative; Aryl iodide building block
EINECS	Contact for details

Quality Control

Our 1-Iodo-2-Chloro-3-Methyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical properties are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.