Description

3-Fluoromethylpiperidine is a versatile fluorinated piperidine derivative, a key building block in modern organic synthesis. Its value lies in the strategic introduction of a fluoromethyl group onto the piperidine scaffold, enabling the fine-tuning of physicochemical properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with unique surface properties.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of bioactive molecules for metabolic and binding studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoromethylpiperidine
CAS No.	116574-73-3
Molecular Formula	C6H12FN
Molecular Weight	117.16 g/mol
Synonyms	3-(Fluoromethyl)piperidine; Piperidine, 3-(fluoromethyl)-; 3-Fluoromethyl-piperidine; 3-Fluoromethyl piperidine; 3-Piperidinylmethyl fluoride; (3-Piperidinyl)methyl fluoride; 116574-73-3; 3-FMP
EINECS	Contact for details

Quality Control

Our 3-Fluoromethylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to minimize exposure to moisture and air. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual ≤ 1.0%; Total ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.