Description

Methyl-4 7 8 9-Tetra-o-Acetyl-2-Thio -n- is a key protected thioglycoside intermediate, essential for the controlled synthesis of complex carbohydrate analogs and nucleoside derivatives. Its value lies in providing a stable, reactive handle for selective glycosylation and further functionalization in advanced organic synthesis. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, carbohydrate-based therapeutics, and novel chemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Used as a key precursor in the study and synthesis of complex oligosaccharides and glycoconjugates.
• Glycosylation Reactions: Serves as a versatile glycosyl donor in stereoselective glycosylation protocols for constructing specific glycosidic linkages.
• Chemical Biology Probes: Enables the creation of labeled or modified sugars for investigating biological recognition and metabolic pathways.
• Process Development: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Methyl-4 7 8 9-Tetra-o-Acetyl-2-Thio -n-
CAS No.	116450-06-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methyl 2-Thio-α/β-D-glucopyranoside Tetraacetate; 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-thio-α-D-glucopyranoside methyl derivative; Methyl 2-Thio-α-D-glucopyranoside Tetraacetate; Methyl 2-Thio-β-D-glucopyranoside Tetraacetate; Methyl 2-S-thioglucoside tetraacetate; 6-Thio-D-glucose derivative tetraacetate methyl glycoside; Protected 2-thioglucose methyl glycoside
EINECS	Contact for details

Quality Control

Our Methyl-4 7 8 9-Tetra-o-Acetyl-2-Thio -n- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term stability, it is recommended to store the product at 2-8°C under an inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.