Description

Fumonisin B1 CAS NO 116355-83-0 is a potent mycotoxin produced primarily by *Fusarium* fungi, notably *Fusarium verticillioides*. This compound is of critical importance for research, regulatory compliance, and quality control in the food and feed industries due to its significant health risks, including carcinogenicity and hepatotoxicity. It is an essential reference standard and analytical reagent for laboratories in the agricultural, food safety, and toxicology sectors, enabling accurate detection, quantification, and study of mycotoxin contamination.

Application

• Analytical Reference Standard: Primary use as a certified calibrant for the quantitative analysis (e.g., HPLC, LC-MS/MS) of fumonisin contamination in foodstuffs like corn, maize, and cereals.
• Food & Feed Safety Testing: Critical component in the development and validation of testing kits, immunoassays (ELISA), and laboratory methods to ensure compliance with global regulatory limits (e.g., FDA, EFSA).
• Toxicological Research: Used in biomedical and agricultural research to study the mechanisms of toxicity, carcinogenicity (e.g., esophageal cancer links), and biochemical impacts of fumonisins.
• Quality Control & Method Development: Serves as a system suitability check and proficiency testing material for laboratories performing mycotoxin analysis, ensuring method accuracy and precision.
• Pharmaceutical Research: Investigated in studies exploring its role in disease models and potential therapeutic targets related to its toxic effects.
• Agricultural Science: Employed in studies focusing on fungal pathogenesis, crop resistance, and the development of mitigation strategies for mycotoxin contamination in the field and during storage.

Basic Information

Product Name	Fumonisin B1
CAS No.	116355-83-0
Molecular Formula	C34H59NO15
Molecular Weight	721.82 g/mol
Synonyms	Fumonisin B1; Macrofusine; FB1; Fusarin C; Toxin from *Fusarium moniliforme*; (2S,2'S)-2,2'-[(5S,6R,7R,9R,11S,16R,18S,19S)-19-Amino-11,16,18-trihydroxy-5,9-dimethylicosane-6,7-diyl]bis[oxy(2-oxoethane-2,1-diyl)]oxymethylene]neopentyl tetrahydro-2H-pyran-2,4,5-triyl triacetate; EINECS 601-143-6
EINECS	601-143-6

Quality Control

Our Fumonisin B1 is produced and handled under strict quality protocols to ensure the highest purity and stability for critical analytical applications. Each batch undergoes comprehensive testing, including identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by HPLC. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, water content, and related substances. Our quality system supports compliance with relevant standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after each use to maintain stability and purity. Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in acetonitrile, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.