Description

Pradimicinone CAS NO 116276-03-0 is a key anthraquinone-derived intermediate in the synthesis of pradimicin antibiotics. This compound matters for its critical role in developing novel antifungal agents with unique mechanisms of action, such as calcium-dependent carbohydrate recognition. It is essential for pharmaceutical R&D teams, medicinal chemists, and manufacturers focused on developing next-generation anti-infective therapies and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of Pradimicin A, FA-2, and other pradimicin-class antifungal antibiotics.
• Medicinal Chemistry Research: Core scaffold for analog development and structure-activity relationship (SAR) studies to enhance antifungal potency and spectrum.
• Antifungal Agent Development: Used in R&D for creating novel agents that target fungal cell wall carbohydrates via a calcium-dependent mechanism.
• Biochemical Tool Compound: Serves as a reference standard and probe in microbiology and pharmacology to study carbohydrate-protein interactions and antifungal modes of action.
• Academic & Institutional Research: Utilized in university and institutional labs for studies on natural product synthesis, antibiotic resistance, and novel therapeutic pathways.

Basic Information

Product Name	Pradimicinone
CAS No.	116276-03-0
Molecular Formula	C31H31NO11
Molecular Weight	593.58 g/mol
Synonyms	Benzo[a]anthracene-7,12-dione, 1,2,3,4,4a,12a-hexah-8,9,10,11-tetrahydroxy-6-(hydroxymethyl)-1,2,3,4-tetrahydro-1,2,3,4,4a,12a-hexahydro-; Pradimicinone aglycon; Pradimicin A aglycone; 4H-Naphtho[2,3-h]chromene-7,12-dione derivative; BMS-181184 aglycon; FA-2M2 aglycon
EINECS	Contact for details

Quality Control

Our Pradimicinone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange-brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.