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9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene CAS NO 115810-14-5
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CAS No.:115810-14-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene is a highly functionalized taxane diterpenoid derivative, representing a key advanced intermediate in complex organic synthesis. This compound matters for its role as a sophisticated building block in the research and development of novel pharmaceutical agents, particularly in oncology and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation therapeutics and exploring structure-activity relationships.
Application
- Pharmaceutical Intermediate: Critical precursor in the semi-synthesis of complex taxane-based drug candidates and analogs for oncology research.
- Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and reduced side effects.
- Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories studying taxane derivatives.
- Biochemical Research: Employed in studies investigating tubulin polymerization inhibition and other cellular mechanisms targeted by taxane compounds.
- Fine Chemical Synthesis: Advanced building block for the synthesis of novel, complex natural product analogs and specialty chemicals.
Basic Information
| Product Name | 9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene |
| CAS No. | 115810-14-5 |
| Molecular Formula | C36H44O9 |
| Molecular Weight | 620.73 g/mol |
| Synonyms | 9α,10β,13α-Triacetoxy-5α-cinnamoyloxytaxa-4(20),11-diene; 5α-Cinnamoyloxy-9α,10β,13α-triacetoxytaxa-4(20),11-diene; Taxa-4(20),11-diene, 9,10,13-triacetoxy-5-cinnamoyloxy-, (5α,9α,10β,13α)-; 115810-14-5; (5α,9α,10β,13α)-9,10,13-Triacetoxy-5-cinnamoyloxytaxa-4(20),11-diene; A key taxane intermediate; Triacetyl cinnamoyl taxadiene derivative. |
| EINECS | Contact for details |
Quality Control
Our 9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability and batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (IR) | Spectrum matches reference |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Single Unknown Impurity (HPLC) | ≤ 1.0% |
| Total Impurities (HPLC) | ≤ 5.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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