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9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene CAS NO 115810-14-5


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CAS No.:115810-14-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene is a highly functionalized taxane diterpenoid derivative, representing a key advanced intermediate in complex organic synthesis. This compound matters for its role as a sophisticated building block in the research and development of novel pharmaceutical agents, particularly in oncology and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation therapeutics and exploring structure-activity relationships.

Application

  • Pharmaceutical Intermediate: Critical precursor in the semi-synthesis of complex taxane-based drug candidates and analogs for oncology research.
  • Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and reduced side effects.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories studying taxane derivatives.
  • Biochemical Research: Employed in studies investigating tubulin polymerization inhibition and other cellular mechanisms targeted by taxane compounds.
  • Fine Chemical Synthesis: Advanced building block for the synthesis of novel, complex natural product analogs and specialty chemicals.

Basic Information

Product Name 9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene
CAS No. 115810-14-5
Molecular Formula C36H44O9
Molecular Weight 620.73 g/mol
Synonyms 9α,10β,13α-Triacetoxy-5α-cinnamoyloxytaxa-4(20),11-diene; 5α-Cinnamoyloxy-9α,10β,13α-triacetoxytaxa-4(20),11-diene; Taxa-4(20),11-diene, 9,10,13-triacetoxy-5-cinnamoyloxy-, (5α,9α,10β,13α)-; 115810-14-5; (5α,9α,10β,13α)-9,10,13-Triacetoxy-5-cinnamoyloxytaxa-4(20),11-diene; A key taxane intermediate; Triacetyl cinnamoyl taxadiene derivative.
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Quality Control

Our 9Alpha,10Beta,13Alpha-Triacetoxy-5Alpha-Cinnamoyloxytaxa-4(20),11-Diene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (HPLC) Retention time corresponds to reference standard
Identification (IR) Spectrum matches reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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