Description

Bistratene A CAS NO 115566-02-4 is a potent and selective macrocyclic lactam compound belonging to the family of protein phosphatase inhibitors. This compound matters for its significant role as a biochemical tool in advanced life science research, particularly in the study of cellular signaling pathways and protein function. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in drug discovery and molecular biology.

Application

• Biochemical Research: Used as a selective inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A) to study cellular processes like cell cycle regulation, signal transduction, and apoptosis.
• Drug Discovery & Target Validation: Serves as a critical pharmacological probe in high-throughput screening assays and target identification studies for oncology and metabolic diseases.
• Academic Research: Employed in university and institutional labs for fundamental research into enzyme kinetics, protein-protein interactions, and post-translational modifications.
• Pharmaceutical Development: Acts as a reference standard or lead compound in the development of novel therapeutic agents targeting specific phosphatase enzymes.
• Cellular & Molecular Biology: Applied in studies investigating the role of phosphatases in neuronal function, muscle contraction, and gene expression.

Basic Information

Product Name	Bistratene A
CAS No.	115566-02-4
Molecular Formula	C30H48N4O6
Molecular Weight	560.73 g/mol
Synonyms	Bistratene A; Bistratene-A; Bistratene A (PP1/PP2A inhibitor); 1H-Pyrrole-2,5-dione, 3,4-dihydro-3-[2-[(1S,4aS,8aS)-1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4-methylene-1-(1-methylethyl)-2-naphthalenyl]ethyl]-4-(1H-pyrrol-2-ylmethyl)-, (3R,4S)-; Protein Phosphatase Inhibitor Bistratene A
EINECS	Contact for details

Quality Control

Our Bistratene A is produced under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation, NMR and MS for structural verification, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.