Description

(2S)-(+)-Glycidyl 4-Nitrobenzoate is a high-purity chiral glycidyl ester derivative, serving as a critical chiral building block and resolving agent in advanced organic synthesis. Its enantiomerically pure structure is essential for introducing stereochemistry into target molecules, enabling the production of optically active intermediates. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs), chiral catalysts, and complex fine chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the asymmetric synthesis of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
• Chiral Resolving Agent: Used for the separation of racemic mixtures to obtain optically pure enantiomers.
• Agrochemical Research & Development: Employed in the synthesis of chiral pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Advanced Material Science: Utilized in the research of chiral polymers and liquid crystals with specific optical properties.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(2S)-(+)-Glycidyl 4-Nitrobenzoate
CAS No.	115459-65-9
Molecular Formula	C10H9NO5
Molecular Weight	223.18 g/mol
Synonyms	(S)-(+)-Glycidyl 4-Nitrobenzoate; (2S)-(-)-2,3-Epoxypropyl 4-Nitrobenzoate; (S)-Glycidyl p-Nitrobenzoate; (2S)-Oxiran-2-ylmethyl 4-nitrobenzoate; p-Nitrobenzoic Acid (S)-Glycidyl Ester; (S)-(+)-Epoxypropyl p-Nitrobenzoate; (S)-(-)-2,3-Epoxy-1-propanol 4-Nitrobenzoate
EINECS	Contact for details

Quality Control

Our (2S)-(+)-Glycidyl 4-Nitrobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR for structural confirmation. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.