Description

(2-Boc-Aminophenyl)Boronic Acid is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a versatile and critical building block in the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boronic acid coupling partner for forming carbon-carbon bonds between aromatic rings, a fundamental reaction in medicinal chemistry.
• Peptidomimetic & PROTAC Synthesis: Used in the construction of complex organic molecules like protease inhibitors and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Research: Employed in the development of novel herbicides and pesticides through structure-activity relationship (SAR) studies.
• Material Science: Acts as a monomer or functionalization agent in the creation of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop selective molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	(2-Boc-Aminophenyl)Boronic Acid
CAS No.	115377-94-1
Molecular Formula	C11H16BNO4
Molecular Weight	237.06 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)phenylboronic acid; N-Boc-2-aminophenylboronic acid; (2-((tert-Butoxycarbonyl)amino)phenyl)boronic acid; BOC-2-Aminophenylboronic Acid; 2-(Boc-amino)benzeneboronic acid; tert-Butyl (2-boronophenyl)carbamate; 2-Aminophenylboronic acid, N-Boc protected
EINECS	Contact for details

Quality Control

Our (2-Boc-Aminophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.