Description

(4As)-8Aβ-(1,3-Dioxolan-2-Yl)Octahydro-2,5-Dimethyl-5α-(4-Methyl-3-Pentenyl)-1(2H)-Naphthalenone is a high-purity, complex organic intermediate with a defined stereochemistry that is critical for advanced synthesis. This compound matters as a key chiral building block in the production of fine chemicals and active pharmaceutical ingredients (APIs), where precise molecular architecture is non-negotiable. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of complex drug candidates, particularly in steroid-like or terpenoid-based therapeutic molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its intricate carbon skeleton for targeted biological activity.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing fragrances, flavors, and other high-value specialty chemicals requiring specific stereocenters.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including catalysis and asymmetric synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(4As)-8Aβ-(1,3-Dioxolan-2-Yl)Octahydro-2,5-Dimethyl-5α-(4-Methyl-3-Pentenyl)-1(2H)-Naphthalenone
CAS No.	115376-32-4
Molecular Formula	C22H36O3
Molecular Weight	348.52 g/mol
Synonyms	8Aβ-(1,3-Dioxolan-2-yl)octahydro-2,5-dimethyl-5α-(4-methyl-3-pentenyl)-1(2H)-naphthalenone; (4aS,5S,8aR)-5-(4-Methylpent-3-en-1-yl)-2,5,8a-trimethyl-4,4a,5,6,7,8-hexahydro-2H-naphthalen-1-one ethylene ketal; 5α-(4-Methyl-3-pentenyl)-2,5-dimethyl-8aβ-(1,3-dioxolan-2-yl)perhydronaphthalen-1-one; Steroid synthesis intermediate; Terpenoid ketal intermediate.
EINECS	Contact for details

Quality Control

Our (4As)-8Aβ-(1,3-Dioxolan-2-Yl)Octahydro-2,5-Dimethyl-5α-(4-Methyl-3-Pentenyl)-1(2H)-Naphthalenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC and structural confirmation by NMR and MS, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.