Description

2-(Trifluoromethyl)-2-Hydroxypropionic Acid is a specialized fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a trifluoromethyl group and a carboxylic acid functionality, makes it a valuable precursor for creating compounds with enhanced properties like metabolic stability and lipophilicity. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly where the introduction of fluorine atoms is desired to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Material Science: Employed in the synthesis of fluorinated polymers or surface modifiers to impart oil-repellency, chemical resistance, or low surface energy characteristics.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the -C(CF3)(OH)CH2COOH moiety into more complex molecular architectures in fine chemical production.

Basic Information

Product Name	2-(Trifluoromethyl)-2-Hydroxypropionic Acid
CAS No.	114715-77-4
Molecular Formula	C4H5F3O3
Molecular Weight	158.08 g/mol
Synonyms	2-Hydroxy-2-(trifluoromethyl)propanoic Acid; 2-(Trifluoromethyl)lactic Acid; α-Hydroxy-α-(trifluoromethyl)propionic Acid; 2-Trifluoromethyl-2-hydroxypropionic Acid; TFHPA; 3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-2-Hydroxypropionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting specifications for research and industrial use. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.