Description

Trimethyl-(3-Trimethylsilyloxiran-2-Yl)Silane is a specialized organosilicon compound featuring both silane and epoxide functional groups. This unique bifunctional structure makes it a valuable synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and fine chemical industries for the development of novel silicon-containing molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring silicon incorporation for enhanced properties.
• Silylating Agent: Used to introduce the trimethylsilyl (TMS) protecting group to alcohols and other sensitive functional groups during multi-step synthetic sequences.
• Epoxide Ring-Opening Reactions: The reactive oxirane ring enables nucleophilic attack, allowing for the construction of more complex molecular architectures with new carbon-oxygen bonds.
• Material Science Research: Employed in the development of novel silicone-based polymers, resins, and hybrid organic-inorganic materials.
• Cross-Coupling Reagents: Acts as a reagent in palladium-catalyzed cross-coupling reactions for carbon-silicon bond formation.
• Asymmetric Synthesis: Potential use in chiral synthesis as a substrate for creating enantiomerically enriched compounds, given its stereogenic center.

Basic Information

Product Name	Trimethyl-(3-Trimethylsilyloxiran-2-Yl)Silane
CAS No.	114693-79-7
Molecular Formula	C8H20O1Si2
Molecular Weight	188.41 g/mol
Synonyms	2-(Trimethylsilyl)oxirane-2-yltrimethylsilane; (3-Trimethylsilyloxiran-2-yl)trimethylsilane; 2-Trimethylsilyl-2-(trimethylsilyloxymethyl)oxirane; Oxirane, 2-(trimethylsilyl)-2-[(trimethylsilyl)methyl]-; TMS Epoxide Silane Derivative; Trimethyl[3-(trimethylsilyl)oxiran-2-yl]silane; 2,2-Bis(trimethylsilyl)oxirane
EINECS	Contact for details

Quality Control

Our Trimethyl-(3-Trimethylsilyloxiran-2-Yl)Silane is manufactured under strict quality protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.