Description

Benzene, 1-(Bromomethyl)-4-(Fluoromethyl)- is a valuable bifunctional aromatic building block containing both bromomethyl and fluoromethyl substituents. This compound is crucial for advanced organic synthesis, enabling the precise introduction of functional groups for further derivatization. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Polymer & Resin Modification: Employed to introduce cross-linking sites or functional handles into polymer backbones for specialty coatings and adhesives.
• Chemical Research & Development: Essential for academic and industrial R&D in exploring new reactions and creating complex molecular architectures.
• Fluorine Chemistry: A versatile precursor for further fluorination reactions or for creating fluorinated analogs of bioactive molecules.

Basic Information

Product Name	Benzene, 1-(Bromomethyl)-4-(Fluoromethyl)-
CAS No.	114657-15-7
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-Bromomethyl-4-fluoromethylbenzene; α-Bromo-α'-fluoro-p-xylene; p-(Bromomethyl)benzyl Fluoride; 4-(Bromomethyl)benzyl Fluoride; (4-(Bromomethyl)phenyl)methanol, 1-fluoro- derivative; 1,4-Bis(bromomethyl)benzene, fluoro analog; p-Xylylene bromide fluoride
EINECS	Contact for details

Quality Control

Our Benzene, 1-(Bromomethyl)-4-(Fluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive halogen and organofluorine groups, it should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.