Description

(E)-3-(tert-Butyldimethylsilyloxy)Propene-1-Yl-Boronic Acid Pinacol Ester 97% is a high-purity, protected boronic ester derivative, a crucial building block in modern synthetic organic chemistry. This compound matters because it provides a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in constructing olefin-containing bioactive scaffolds.
• Agrochemical Synthesis: Used in creating novel active ingredients for crop protection agents through palladium-catalyzed coupling.
• Advanced Materials Research: Employed in the development of organic electronic materials, liquid crystals, and polymers requiring specific olefinic linkages.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile coupling partner with aryl or vinyl halides to form new C-C bonds with retention of the alkene geometry.
• Chemical Biology & Proteomics: Can be utilized in bioconjugation strategies or as a precursor for activity-based probes.
• Academic & Process R&D: Essential for methodological development and scaling novel synthetic routes in laboratory and pilot-scale settings.

Basic Information

Product Name	(E)-3-(tert-Butyldimethylsilyloxy)Propene-1-Yl-Boronic Acid Pinacol Ester 97%
CAS No.	114653-19-9
Molecular Formula	C15H31BO3Si
Molecular Weight	298.31 g/mol
Synonyms	(E)-3-[(tert-Butyldimethylsilyl)oxy]-1-propen-1-ylboronic acid pinacol ester; (E)-3-(tert-Butyldimethylsiloxy)allylboronic acid pinacol ester; (E)-3-(TBDMSO)allylboronic acid pinacol ester; trans-3-(tert-Butyldimethylsilyloxy)prop-1-en-1-ylboronic acid pinacol ester; (E)-3-(tert-Butyldimethylsilyloxy)allylboronic acid pinacol ester; (E)-3-(TBDMS-oxy)allyl-Bpin; (E)-3-(tert-Butyldimethylsilanyloxy)-prop-1-enyl-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our (E)-3-(tert-Butyldimethylsilyloxy)Propene-1-Yl-Boronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, isomeric purity, and assay. Certificates of Analysis (COA) with detailed specifications are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 98.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.