Description

2-Amino-3-Bromobenzonitrile is a versatile brominated aniline derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a nitrile group adjacent to a bromine atom, makes it a valuable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific mode-of-action properties.
• Material Science: Used in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing and donating capabilities.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Chemistry: Fundamental starting material for constructing indoles, quinolines, and other nitrogen-containing heterocycles important in medicinal chemistry.

Basic Information

Product Name	2-Amino-3-Bromobenzonitrile
CAS No.	114344-60-4
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	3-Bromo-2-aminobenzonitrile; 2-Amino-3-bromobenzene carbonitrile; 3-Bromoanthranilonitrile; 2-Cyano-6-bromoaniline; Benzonitrile, 2-amino-3-bromo-; 6-Bromo-2-aminobenzonitrile; 3-Bromo-2-cyanobenzenamine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and Good Manufacturing Practice (GMP) guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (nitrogen or argon) is recommended for optimal long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.