Description

4,5-o-(1-Methylethylidene)-3,6-Bis-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-Dl-Myo-Inositol CAS NO 114218-25-6 is a sophisticated, multi-protected derivative of myo-inositol, a key sugar alcohol and biochemical precursor. This compound matters as a critical advanced synthetic intermediate in the production of complex bioactive molecules, offering precise stereochemical control and functional group protection. It is primarily needed by pharmaceutical R&D and fine chemical synthesis laboratories for developing novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex inositol phosphate analogs and glycosylphosphatidylinositol (GPI) anchors for drug discovery.
• Chemical Biology Research: Used in the preparation of labeled or modified inositols to study cellular signaling pathways, particularly those involving phosphoinositides.
• Chiral Auxiliary/Synthon: Serves as a protected chiral scaffold for the asymmetric synthesis of natural products and other stereochemically complex targets.
• Glycochemistry: Employed in the synthesis of complex carbohydrate derivatives and glycomimetics due to its protected hydroxyl groups.
• Process Development: Used in scaling up synthetic routes for bioactive inositol derivatives under controlled and protected conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4,5-o-(1-Methylethylidene)-3,6-Bis-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-Dl-Myo-Inositol
CAS No.	114218-25-6
Molecular Formula	C46H48O6
Molecular Weight	696.88 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-3,4-di-O-benzyl-myo-inositol (1-O-trityl derivative); 1-O-Trityl-3,4-di-O-benzyl-myo-inositol 5,6-O-isopropylidene acetal; DL-myo-Inositol, 4,5-O-(1-methylethylidene)-3,6-bis-O-(phenylmethyl)-1-O-(triphenylmethyl)-; 1-O-Triphenylmethyl-3,4-di-O-benzyl-myo-inositol 5,6-acetonide; Protected myo-inositol derivative; Trityl-benzyl-isopropylidene-myo-inositol
EINECS	Contact for details

Quality Control

Our 4,5-o-(1-Methylethylidene)-3,6-Bis-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-Dl-Myo-Inositol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs in advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.