Description

Methyl 2-Chloro-3-oxopentanoate is a versatile chlorinated ketoester building block of significant importance in advanced organic synthesis. Its reactive carbonyl and ester functionalities, activated by the adjacent chlorine atom, make it a critical precursor for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs) and specialized intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of heterocyclic compounds, including pyrazoles and isoxazoles, which are core structures in various drug candidates.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging its reactive site for side-chain incorporation.
• Chemical Research & Development: Used in academic and industrial R&D for method development and exploring new reaction pathways involving α-halo carbonyl compounds.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances where specific chiral or functionalized backbones are required.

Basic Information

Product Name	Methyl 2-Chloro-3-oxopentanoate
CAS No.	114192-09-5
Molecular Formula	C6H9ClO3
Molecular Weight	164.59 g/mol
Synonyms	Methyl 2-chloro-3-oxovalerate; 2-Chloro-3-oxopentanoic acid methyl ester; Methyl 2-chloro-3-oxopentanoate; 3-Oxopentanoic acid, 2-chloro-, methyl ester; 2-Chloro-3-oxovaleric acid methyl ester; Methyl α-chloroacetoacetate (related); Methyl 2-chloro-3-oxobutanoate homologue
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-3-oxopentanoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.