Description

(R)-Trichostatic Acid CAS NO 114127-18-3 is a high-purity chiral building block and pharmaceutical intermediate of significant importance in modern organic synthesis. Its value lies in its specific stereochemistry, which is critical for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop products with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, particularly in oncology and metabolic disease research.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Development: Serves as a precursor in the creation of enantiopure pesticides and herbicides with improved efficacy and environmental profiles.
• Biochemical Research: Employed in studies of enzyme mechanisms and as a standard for analytical method development in chiral separations.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	(R)-Trichostatic Acid
CAS No.	114127-18-3
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	(R)-Trichostatin Acid; (R)-TSA; (R)-[4-(Dimethylamino)phenyl]-5-oxo-2,4-pentadienoic Acid; (R)-7-[4-(Dimethylamino)phenyl]-4,6-heptadienoic acid-4-hydroxy-7-oxo; (2E,4E)-5-[4-(Dimethylamino)phenyl]-2,4-pentadienoic acid, (R)-; (R)-(-)-Trichostatin A Acid
EINECS	Contact for details

Quality Control

Our (R)-Trichostatic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.