Description

N,o-Bis(Allyldimethylsilyl)-2,2,2-trifluoroacetamide is a specialized organosilicon reagent featuring both allyl and trifluoroacetamide functionalities. This compound is valued for its role as a versatile silylating agent and protecting group in advanced synthetic chemistry, particularly for sensitive or complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel compounds and intermediates.

Application

• Silylating Agent: Used for the protection of hydroxyl, amino, and other labile functional groups in multi-step organic synthesis.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Employed in the development of novel pesticides, herbicides, and plant growth regulators.
• Material Science Research: Acts as a precursor or modifier in the development of silicon-based polymers and advanced functional materials.
• Analytical Derivatization: Used to enhance the volatility or detectability of compounds for Gas Chromatography (GC) and Mass Spectrometry (MS) analysis.
• Process Chemistry: Applied in scalable manufacturing processes requiring selective protection/deprotection strategies.

Basic Information

Item	Details
Product Name	N,o-Bis(Allyldimethylsilyl)-2,2,2-trifluoroacetamide
CAS No.	113996-89-7
Molecular Formula	C₁₃H₂₄F₃NOSi₂
Molecular Weight	323.51 g/mol
Synonyms	N,O-Bis(allyldimethylsilyl)trifluoroacetamide; Allyldimethylsilyl Trifluoroacetamide; BSA-TFA; N,O-Bis(allyldimethylsilyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N,O-bis[(2-propen-1-yl)dimethylsilyl]acetamide; (Allyldimethylsilyl) Trifluoroacetamide Reagent; TFA Silylating Agent (Allyl); Contact for details on EINECS

Quality Control

Our N,o-Bis(Allyldimethylsilyl)-2,2,2-trifluoroacetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including NMR, GC, and HPLC, to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.