Description

Benzaldehyde, 5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-fluoro- is a high-value, organosilicon-protected benzaldehyde derivative designed for advanced synthetic chemistry. This compound matters as a key protected intermediate, offering enhanced stability and precise reactivity control for the synthesis of complex fluorinated molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom and protected phenol enhance bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced organic materials requiring specific fluorinated aromatic units.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and novel fluorination methodologies in academic and industrial R&D.
• Fine Chemical Production: Acts as a protected intermediate in multi-step syntheses of complex flavors, fragrances, and dyes.

Basic Information

Product Name	Benzaldehyde, 5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-fluoro-
CAS No.	113984-67-1
Molecular Formula	C13H19FO2Si
Molecular Weight	254.37 g/mol
Synonyms	2-Fluoro-5-[(tert-butyldimethylsilyl)oxy]benzaldehyde; 5-[(tert-Butyldimethylsilyl)oxy]-2-fluorobenzaldehyde; 2-Fluoro-5-((tert-butyldimethylsilyl)oxy)benzaldehyde; 2-Fluoro-5-hydroxybenzaldehyde TBDMS ether; TBDMS ether of 2-Fluoro-5-hydroxybenzaldehyde; 5-(tert-Butyldimethylsiloxy)-2-fluorobenzaldehyde; 2-Fluoro-5-(tert-butyldimethylsilyloxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our production of Benzaldehyde, 5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-fluoro- adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for critical R&D and scale-up applications. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.