Description

(2Z)-2-Hydroxy-4-(4-Methylphenyl)-4-Oxobut-2-Enoic Acid is a specialized organic compound belonging to the class of β-keto acids. This chemical serves as a valuable building block and synthetic intermediate in advanced organic synthesis, prized for its unique molecular structure that enables the formation of complex heterocycles and functionalized aromatic systems. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those with anti-inflammatory or central nervous system activity.
• Fine Chemical Synthesis: Building block for creating complex molecules used in agrochemicals, dyes, and functional materials.
• Research & Development: Used in academic and industrial labs for method development and exploring new chemical reactions involving β-keto acid chemistry.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chelating ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	(2Z)-2-Hydroxy-4-(4-Methylphenyl)-4-Oxobut-2-Enoic Acid
CAS No.	113282-74-9
Molecular Formula	C11H10O5
Molecular Weight	222.19 g/mol
Synonyms	(Z)-2-Hydroxy-4-(p-tolyl)-4-oxobut-2-enoic acid; 4-(4-Methylphenyl)-2,4-dioxobut-2-enoic acid; 2-Hydroxy-4-(4-methylphenyl)-4-oxo-2-butenoic acid; p-Methylbenzoylpyruvic acid; 4-Oxo-4-(p-tolyl)-2-butenoic acid; β-Keto acid derivative
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and potency. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our manufacturing processes are designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.