Description

7-Iodo Sancycline is a chemically modified tetracycline derivative, specifically a halogenated analog of sancycline. This compound is of significant interest in pharmaceutical research and development as a key intermediate for synthesizing novel tetracycline-class antibiotics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation antimicrobial agents to address drug-resistant bacterial infections.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel tetracycline antibiotics.
• Antimicrobial Research: Used in R&D to study structure-activity relationships (SAR) and develop compounds against resistant bacterial strains.
• Chemical Biology Probe: Acts as a tool compound to investigate bacterial protein synthesis inhibition mechanisms.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and microbiology.

Basic Information

Product Name	7-Iodo Sancycline
CAS No.	113164-67-3
Molecular Formula	C₂₂H₂₃IN₂O₈
Molecular Weight	594.34 g/mol
Synonyms	7-Iodo-6-demethyl-6-deoxytetracycline; 7-Iodo-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-Iodo-6-demethyl-6-deoxy-5-oxytetracycline; 7-Iodosancycline; 7-Iodo-DMDOT
EINECS	Contact for details

Quality Control

Our 7-Iodo Sancycline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.