Description

Ethyl 1-tert-Butyl-5-Chloro-1H-Pyrazole-4-Carboxylate is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular construction. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Active Ingredient Precursor: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex heterocyclic compounds and libraries for screening.
• Material Science Research: Investigated as a precursor for functional materials, including ligands for catalysis and components in organic electronics.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and chemical process development projects.

Basic Information

Product Name	Ethyl 1-tert-Butyl-5-Chloro-1H-Pyrazole-4-Carboxylate
CAS No.	112779-13-2
Molecular Formula	C10H15ClN2O2
Molecular Weight	230.69 g/mol
Synonyms	1-(1,1-Dimethylethyl)-5-chloro-1H-pyrazole-4-carboxylic acid ethyl ester; 5-Chloro-1-tert-butyl-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 5-chloro-1-tert-butyl-1H-pyrazole-4-carboxylate; 1-tert-Butyl-5-chloropyrazole-4-carboxylic acid ethyl ester; 112779-13-2; UNII-9V6D8K8Q3F; 9V6D8K8Q3F
EINECS	Contact for details

Quality Control

Our Ethyl 1-tert-Butyl-5-Chloro-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.