Description

1-(Trifluoromethyl)Cyclopropanamine is a versatile fluorinated cyclopropylamine building block of significant interest in advanced organic synthesis. Its unique structure, combining a strained cyclopropane ring with a trifluoromethyl group, makes it a critical intermediate for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms and cyclopropyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with unique surface properties or stability.
• Fluorine Chemistry Building Block: An essential starting material for introducing the trifluoromethylcyclopropyl motif into more complex molecular architectures.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclopropanamine
CAS No.	112738-67-7
Molecular Formula	C4H6F3N
Molecular Weight	125.09 g/mol
Synonyms	1-(Trifluoromethyl)cyclopropanamine; 1-Amino-1-(trifluoromethyl)cyclopropane; 1-(Trifluoromethyl)cyclopropylamine; α-(Trifluoromethyl)cyclopropanamine; Cyclopropanamine, 1-(trifluoromethyl)-; 1-Cyclopropyl-2,2,2-trifluoroethylamine (tautomeric form); Trifluoromethylcyclopropylamine
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.