Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, cis- (9Ci) is a specialized, high-purity aldehyde derivative featuring a protected dioxolane ring system. This compound matters as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemistry. It is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-quality intermediates for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereochemically-defined pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new asymmetric catalytic reactions.
• Flavor & Fragrance Chemistry: Employed in the synthesis of sophisticated aroma chemicals and natural product analogs.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Academic & R&D Laboratories: A crucial reagent for methodological studies in organic chemistry and total synthesis projects.

Basic Information

Item	Detail
Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, cis- (9Ci)
CAS No.	112709-69-0
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4S,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (cis)-2,2,5-Trimethyl-1,3-dioxolane-4-carbaldehyde; 2,2,5-Trimethyl-4-formyl-1,3-dioxolane, cis-; cis-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (4S-cis)-2,2,5-Trimethyl-4-dioxolanylcarboxaldehyde; 1,3-Dioxolane-4-carboxaldehyde, 2,2,5-trimethyl-, (4S-cis)-; 4-Formyl-2,2,5-trimethyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, cis- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.