Description

Benzene, 2-Bromo-4-Fluoro-1-(1-Methylethyl)- is a specialized halogenated aromatic compound, recognized as a valuable building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on an isopropylbenzene core, makes it a critical intermediate for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates which often exhibit enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of halogen atoms can significantly alter biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated organic electronic materials, contributing to the development of next-generation displays and lighting technologies.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D labs for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate to develop new catalytic methodologies.
• Specialty Polymer Modification: Utilized to introduce halogenated aromatic groups into polymer chains, modifying properties like flame retardancy, refractive index, and chemical resistance for high-performance materials.

Basic Information

Product Name	Benzene, 2-Bromo-4-Fluoro-1-(1-Methylethyl)-
CAS No.	112611-88-8
Molecular Formula	C9H10BrF
Molecular Weight	217.08 g/mol
Synonyms	2-Bromo-4-fluoro-1-isopropylbenzene; 1-Bromo-2-fluoro-5-isopropylbenzene; 2-Bromo-4-fluorocumene; 1-Isopropyl-2-bromo-4-fluorobenzene; 5-Bromo-2-fluorocumene; (2-Bromo-4-fluorophenyl)propane; Cumene, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our production of Benzene, 2-Bromo-4-Fluoro-1-(1-Methylethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (GC, HPLC, NMR) to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.