Description

4-Sulfocalix[4]arene is a water-soluble, sulfonated derivative of calix[4]arene, a well-known supramolecular host molecule. This compound is valued for its exceptional ability to form stable complexes with a wide range of cationic and neutral organic guests in aqueous media. It is a critical material for researchers and manufacturers in the fields of chemical sensing, catalysis, and pharmaceutical formulation, where selective molecular recognition and encapsulation are required.

Application

• Molecular Recognition & Sensing: Acts as a key component in the development of chemical sensors and electrodes for detecting metal ions, organic amines, and pharmaceuticals.
• Catalysis & Reaction Modulation: Used as a phase-transfer catalyst or a nano-reactor to enhance reaction rates and selectivity in aqueous-organic biphasic systems.
• Drug Delivery Systems: Employed to improve the solubility, stability, and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) through host-guest complexation.
• Environmental Remediation: Applied in extraction and separation processes for the removal of heavy metal ions or organic pollutants from wastewater.
• Analytical Chemistry: Serves as a chiral selector or a stationary phase modifier in capillary electrophoresis and chromatography for enantiomer separation.
• Material Science: Utilized in the fabrication of functional surfaces, membranes, and nanomaterials with specific molecular binding properties.

Basic Information

Item	Details
Product Name	4-Sulfocalix[4]arene
CAS No.	112269-92-8
Molecular Formula	C28H24O16S4
Molecular Weight	744.74 g/mol
Synonyms	p-Sulfonatocalix[4]arene; Calix[4]arenesulfonic Acid; Sulfonated Calix[4]arene; 25,26,27,28-Tetrahydroxycalix[4]arene-5,11,17,23-tetrasulfonic Acid; SC4A; 4-SC4A; Calixarene Sulfonate; Water-Soluble Calixarene
EINECS	Contact for details

Quality Control

Every batch of 4-Sulfocalix[4]arene is produced and tested under a strict quality management system. We ensure compliance with high-purity research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of water.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% aqueous solution)	2.0 - 4.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.