Description

(+)-Diisopinocampheyl Chloroborane is a highly versatile and enantiomerically pure chiral borane reagent. Its core value lies in its exceptional ability to induce stereoselectivity in organic synthesis, making it a critical tool for producing optically active intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity chiral building blocks.

Application

• Asymmetric Synthesis: A premier chiral reducing agent for the enantioselective reduction of prochiral ketones to secondary alcohols.
• Pharmaceutical Intermediates: Key reagent in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex natural products.
• Agrochemical Development: Used to create enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the manufacture of high-value chiral flavors, fragrances, and specialty materials.
• Methodology Research: A standard reagent in academic and industrial laboratories for developing new catalytic and stoichiometric asymmetric transformations.
• Chiral Auxiliary Preparation: Serves as a precursor for other chiral boron-based reagents and catalysts.

Basic Information

Product Name	(+)-Diisopinocampheyl Chloroborane
CAS No.	112246-73-8
Molecular Formula	C20H34BCl
Molecular Weight	320.75 g/mol
Synonyms	(+)-DIP-Chloride; (1R)-(-)-Diisopinocampheylchloroborane; (1R)-(-)-B-Chlorodiisopinocampheylborane; (1R,2S,5R)-(-)-2-Chloro-3,7,7-trimethylbicyclo[3.1.1]hept-2-ylborane; DIP-Cl; Ipc2BCl; Chiral chloroborane reagent
EINECS	Contact for details

Quality Control

Our (+)-Diisopinocampheyl Chloroborane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing purity, assay, enantiomeric excess (ee), and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. The product is moisture-sensitive and easily oxidized; containers must be kept sealed and handled under anhydrous conditions to maintain purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution or solid
Identification (IR)	Conforms to structure
Assay (NMR/Titration)	≥ 95.0%
Enantiomeric Excess (ee)	≥ 99.0%
Optical Rotation [α]	Contact for details
Solvent (if supplied as solution)	Specified (e.g., Hexane, Toluene)
Concentration (if supplied as solution)	Specified (e.g., 1.0 M)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.