Description

Ethyl (2-Hydroxy-2-Adamantyl)Acetate is a high-value, functionalized adamantane derivative that serves as a critical advanced intermediate in organic synthesis. This compound is prized for its unique polycyclic cage structure, which imparts exceptional stability and lipophilicity to target molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), complex agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the development of novel, high-performance pesticides and herbicides, where the adamantyl group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or additive for creating specialty polymers with enhanced thermal stability, rigidity, and chemical resistance.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D, enabling the construction of complex molecular architectures for catalysis and supramolecular chemistry.
• Ligand and Catalyst Development: The functional groups allow for modification into chiral ligands or organocatalysts used in asymmetric synthesis.
• Cosmetic Ingredient Precursor: Potential intermediate for synthesizing UV absorbers or stabilizers in high-end cosmetic formulations.

Basic Information

Product Name	Ethyl (2-Hydroxy-2-Adamantyl)Acetate
CAS No.	112181-97-2
Molecular Formula	C₁₄H₂₂O₃
Molecular Weight	238.32 g/mol
Synonyms	Ethyl 2-(2-Hydroxyadamantan-2-yl)acetate; 2-(2-Hydroxy-2-adamantyl)acetic Acid Ethyl Ester; Acetic Acid, 2-(2-Hydroxy-2-adamantyl)-, Ethyl Ester; Adamantaneacetic acid, 2-hydroxy-, ethyl ester; Ethyl (2-hydroxyadamantan-2-yl)acetate; 2-(2-Hydroxy-2-adamantyl)ethyl acetate (common misnomer); 1-Ethoxycarbonylmethyl-1-hydroxyadamantane
EINECS	Contact for details

Quality Control

Every batch of Ethyl (2-Hydroxy-2-Adamantyl)Acetate is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.